School of Health Sciences: Recent submissions

Now showing items 21-40 of 79

Blood Glucose Lowering Effect and Safety of the Aqueous Leaf Extracts of Zanha africana

Abdirahman, YA.; Juma., KK.; Makori., WA.; Agyirifo, DS.; Ngugi, MP.; Gathumbi, PK.; Ngeranwa, JJN.; Njagi, ENM. (Pharmaceutica Analytica Acta, 2015-09-30)

Zanha africana has been used traditionally to manage many diseases including diabetes, however, its antidiabetic activity and safety is not well evaluated. The aim of this study was to determine in vivo hypoglycemic ...
Impact of Prejudice on Caregivers of People with Mental Illness in Uasin Gishu County, Kenya

Ombok, Caroline A.; Kareithi, Joram; Wandere, Donald (Redfame Publishing, 2022-08-30)

Negative beliefs and preconceived opinions on mental illness, which are not based on reason or actual experience, play a significant role in determining treatment and health-seeking behaviour by caregivers of people with ...
Cultural Adaptation Practices in Health Seeking Behaviour by Caregivers of Mentally Ill Patients in Uasin Gishu County, Kenya

Ombok, Caroline Atieno; Kareithi, Joram; Wandere, Donald (Scientific Research Publishing, 2022-05-27)

For the mentally ill, cultural prescriptions and proscriptions play a major role in their caregiver’s health-seeking behaviour. Most ill patients seek treatment in hospital setting but still, culturally adaptive options ...
Growth Performance of Domesticated Prunus africana Population in Muguga, Kiambu County, Kenya

Nyamai, DW.; Mawia, AM.; Wambua, FK.; Abdirahman, YA.; Osano, K.; Lagat, R.; Mumbi, B.; Arika, W.; Juma, KK.; Anyango, E.; Mulugeta, M.; Ngugi, MP.; Muchugi, A.; Ng’ang’a, M.; Burugu, MW. (ResearchGate, 2015-10-23)

Prunus africana (Hook. f.) is an evergreen tree that grows in African mountains. The species’ bark and bark extracts are used for the treatment of benign prostate hyperplasia. High demand for the bark and bark extracts ...
In-Vivo Anti-hyperglycemic Activity and Safety of The Aqueous Stem Bark Extracts of Aloe secundiflora

Abdirahman, YA.; Juma., KK.; Nyamai, DW.; Njagi, JM.; Agyirifo, DS.; Ngugi, MP.; Gathumbi, PK.; Ngeranwa, JJN.; Njagi, ENM. (Medicinal & Aromatic Plants, 2013-10-05)

Aloe secundiflora has been used traditionally to manage many diseases including diabetes, however, its antidiabetic activity and safety is not well evaluated. The aim of this study was to determine in vivo hypoglycemic ...
Antinociceptive Activities of Acetone leaf Extracts of Carissa Spinarum in Mice

Mworia, JK.; Gitahi, SM.; Juma, KK.; Njagi, JM.; Mwangi, BM.; Aliyu, U.; Njoroge, WA.; Mwonjoria, KJ.; Mawia, AM.; Nyamai, DW.; Ngugi, MP.; Ngeranwa, JJN. (Medicinal & Aromatic Plants, 2016-10-26)

Despite the progress that has occurred in recent years in the development of therapies for pain, there is still a need for effective and potent analgesics for pain. Pain is defined as unpleasant feeling essential for ...
Determination of Hematological Effects of Methanolic Leaf Extract of S. incanum in Normal Mice

Muriithi, Njagi J.; Maina, Gitahi S.; Mugendi, Njagi M.; Maina, Mwangi B.; Kiambi, Mworia J.; Juma, Kelvin K.; Umar, Aliyu; Mwonjoria, John K.; Njoroge, Ann W.; Abdirahman, YA.; Piero, Ngugi M.; Njagi, Eliud NM. (Pharmaceutica Analytica Acta, 2015-10-16)

Medicinal plants and herbs have been used for ages for the purposes of enhancing and maintaining health and organic resistance against body infection. This is due to their ready availability and arguably efficacious ...
In Vivo Antianaemic Effect and Safety of Aqueous Extracts of Erythrina abyssinica and Zanthoxylum usambarensis in Mice Models

Musyoka, Thomas M.; Nyamai, Dorothy W.; Arika, Wycliffe M.; Juma, Kelvin K.; Nzioka, Mutua D.; Maina, David.; Waithaka, Stanely K.; Ngugi, Mathew P.; Orinda, George O.; Karau, Geoffrey M.; Njagi, Eliud NM. (Journal of Hematology & Thromboembolic Diseases, 2016-05-13)

This study was carried out to determine the hematinic effects and long term safety of Zanthoxylum usambarensis and Erythrina abyssinica in mice. Aqueous stem extracts of Z. usambarensis and E. abyssinica were screened ...
CD38 as Surrogate Marker for HIV Infection in Antiretroviral Naive and Antiretroviral Experienced Patients in Kenya

Njuguna, AN.; Juma, KK.; Waihenya, RK; Mpoke, S.; Mbuchi, M.; Muthami, L; Mathaai, R.; Otieno, P.; Nyakundi, P. (Advances in Molecular Diagnostics, 2016-06-17)

Human Immunodeficiency Virus (HIV) patient management continues to be a challenge all over the world. CD4 absolute counts and viral load are the gold standard tools for monitoring of HIV-1 disease. However, the use of ...
Abundance and Symbiotic Potential of Common Bean (Phaseolus vulgaris) Nodule Associated Bacteria in Western Kenya Soil

Wekesa, Clabe.; Okun, Daniel.; Juma, Kelvin.; Shitabule, Dalmas.; Okoth, Patrick.; Nyongesa, Peter.; Katoo, Athanas; Mulama, Samuel; Wamalwa, Emily.; Mahalo, Clarice.; Koyo, Moses; Rotich, Aron; Kawaka, Fanuel.; Muoma, John. (MAYFEB Journal of Agricultural Science, 2016)

Plant growth-promoting Rhizobacteria are beneficial native soil bacteria that colonize plant roots and result in increased plant growth. Those that colonise the nodules of legumes are known as nodule associated bacteria. ...
Anti-inflammatory activity of craterostigma pumilum (hochst) is associated with hyperalgesia

Mwonjoria, John K.; Umar, Aliyu.; Juma, Kevin K.; Kahiga, Titus M.; Piero, Ngugi M.; Mburu, David.; Wanyonyi, Alphonse W.; Githinji, Charles G.; Ngeranwa, Joseph N. (International Journal of Pharmacology and Toxicology, 2016)

Inflammation and pain are ubiquitous signs and symptoms of a large number of ailments affecting humanity. There are equally as many methods and substances that are used as remedies for the conditions. Examples of remedies ...
Paediatric and Young Adults Reference Values for Renal, Cardiac and Pancreatic Function Tests for the Population of Taita Taveta County

Gitimu, MR.; Njangiru, KI.; Mutua, ND.; Waithaka, KS.; Juma, KK.; Ndungu, WC.; Mwawasi, J; Charo, MW; Parmal, D; Ngeranwa, NJ; Njagi, ENM. (ResearchGate, 2016-09-30)

Reference interval in biochemistry laboratories provides guidelines to the clinicians to interpret the client’s results. A population of 120 healthy individuals are required in establishing reference ranges to achieve the ...
Potential Anti-diabetic Effects and Safety of Aqueous Extracts of Urtica dioica Collected from Narok County, Kenya

Mukundi, Mwangi J.; Mwaniki, Njagi EN.; Piero, Ngugi M.; Murugi, Njagi J.; Juma, Kelvin K.; Yusuf, Abdirahman A.; Mwonjoria, John K.; Ngetich, Alex K.; Agyirifo, Daniel S.; Gathumbi, Peter K.; Muchugi, Alice N. (Pharmaceutica Analytica Acta, 2017-05-30)

Drug bio screening for potential anti-diabetics is scientifically motivated by the desire to discover newer, safer and affordable drugs that complement conventional strategies for management of diabetes. Urtica dioica ...
EVALUATION OF ANALGESIC, ANTI-INFLAMMATORY AND TOXIC EFFECTS OF LANTANA CAMARA L.

Sore, Millycent A.; Mwonjoria, John K.; Juma, Kelvin K.; Piero, Ngugi M.; Mwaniki, Njagi E.N. (Research gate, 2017-04-18)

Lantana camara has been used traditionally to manage several diseases such as wound healing, inflammation and pain. However, its efficacy and safety has not been scientifically evaluated and clarified. The aim of this ...
Evidence Based Targeting of Cytokines for Conventional and the Potential Phytotherapies in Management of Rheumatoid Arthritis

Mutua, David N.; Juma, Kelvin K.; Gitimu, MR.; Ireri, MM. (Journal of Arthritis, 2017-04-10)

Rheumatoid arthritis is an autoimmune disease that leads to chronic, systemic inflammatory reaction that primarily affects synovial joints. Current cytokine based therapies are effective and safe. However, they have ...
Genetic Characterization of Rhizosphere Bacteria that Inhabit Common Bean Nodules in Western Kenya Soils

Wekesa, Clabe; Muoma, John.; Ombori, Omwoyo; Maingi, John.; Okun, Daniel.; Juma, Kelvin; Okoth, Patrick.; Wamalwa, Emily.; Kollenberg, Mario.; Mauti, Eliakim. (Research gate, 2017-02-11)

Background: With the increasing world population, there is increasing demand for food. This has led to overuse of agricultural farms causing reduced soil fertility and accumulation of phytopathogens. Inorganic fertilizers ...
VALIDITY AND RELIABILITY OF CHILD AND ADOLESCENT DISRUPTIVE BEHAVIOUR INVENTORY IN NAIROBI, KENYA

Changorok, Susan.; Manya, Stephen W.; Juma, Kelvin K. (International Journal of Social Science and Economic Research, 2018-12-12)

The purpose of the study was to determine the validity and reliability of the Child and Adolescent Disruptive Behaviour Inventory (CADBI) developed by Burns (2001).In the study Quasi-experimental research design was ...
Predictors of Plasmodium falciparum Infection in the First Trimester Among Nulliparous Women From Kenya, Zambia, and the Democratic Republic of the Congo

Leuba, Sequoia I.; Westreich, D.; Bose, Carl L.; Powers, Kimberly A.; Olshan, Andy; Taylor, Steve M.; Tshefu, A.; Lokangaka, A.; Carlo, Waldemar A.; Chomba, E.; Liechty, Edward A.; Bucher, Sherri L.; Esamai, F.; Jessan, S.; Saleem, S.; Goldenberg, Robert L.; Moore, J.; Nolen, T.; Hemingway-Foday, J.; McClure, Elizabeth M.; Koso-Thomas, M.; Derman, Richard J.; Hoffman, M.; Bauserman, M. (Oxford University Press, 2021-12-09)

Background. Malaria can have deleterious effects early in pregnancy, during placentation. However, malaria testing and treatment are rarely initiated until the second trimester, leaving pregnancies unprotected in the first ...
Male Lived Experience of Domestic Violence in the Households, Nyeri County, Kenya

Muia, Catherine Mwikali; Masinde, Prof. Jamine; Rono, Dr. Joseph K. (International Journal of Research and Innovation in Social Science, 2022-02)

Domestic violence against men (DVAM) remains a private affair in many Africa countries. That rarely draws attention of legislators, policy makers and members of society as it is with other family members. The study ...
Knowledge, attitude and practices of pregnant women related to COVID-19 infection: A cross- sectional survey in seven countries from the Global Network for Women's and Children's Health

Naqvi, F.; Naqvi, S.; Billah, Sk M.; Saleem, S.; Fogleman, E.; Peres- da- Silva, N.; Figueroa, L.; Mazariegos, M.; Garces, Ana L.; Patel, A.; Das, P.; Kavi, A.; Goudar, Shivaprasad S.; Esamai, F.; Chomba, E.; Lokangaka, A.; Tshefu, A.; Haque, R.; Siraj, S.; Yousaf, S.; Bauserman, M.; Liechty, Edward A.; Krebs, Nancy F.; Derman, Richard J.; Carlo, Waldemar A.; Petri Jr, William A.; Hibberd, Patricia L.; Koso- Thomas, M.; Bann, Carla M.; McClure, Elizabeth M.; Goldenberg, Robert L. (BJOG, 2022-01-20)

Objective: We sought to understand knowledge, attitudes and practices (KAP) re-garding COVID-19 in pregnant women in seven low and middle-income countries (LMIC).Design: Population-based prospective, observational ...

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