Browsing School of Health Sciences by Title

Now showing items 1-20 of 79

Abundance and Symbiotic Potential of Common Bean (Phaseolus vulgaris) Nodule Associated Bacteria in Western Kenya Soil

Wekesa, Clabe.; Okun, Daniel.; Juma, Kelvin.; Shitabule, Dalmas.; Okoth, Patrick.; Nyongesa, Peter.; Katoo, Athanas; Mulama, Samuel; Wamalwa, Emily.; Mahalo, Clarice.; Koyo, Moses; Rotich, Aron; Kawaka, Fanuel.; Muoma, John. (MAYFEB Journal of Agricultural Science, 2016)

Plant growth-promoting Rhizobacteria are beneficial native soil bacteria that colonize plant roots and result in increased plant growth. Those that colonise the nodules of legumes are known as nodule associated bacteria. ...
Anti-inflammatory activity of craterostigma pumilum (hochst) is associated with hyperalgesia

K. Mwonjoria, John; Umar, Aliyu; K. Juma, Kevin; M. Kahiga, Titus; M. Ngugi, Piero; Mburu, David; W. Wanyonyi, Alphonse; G. Githinji, Charles; N. Ngeranwa, Joseph (ResearchGate, 2016-01)

Inflammation and pain are ubiquitous signs and symptoms of a large number of ailments affecting humanity. There are equally as many methods and substances that are used as remedies for the conditions. Examples of remedies ...
Anti-inflammatory activity of craterostigma pumilum (hochst) is associated with hyperalgesia

Mwonjoria, John K.; Umar, Aliyu.; Juma, Kevin K.; Kahiga, Titus M.; Piero, Ngugi M.; Mburu, David.; Wanyonyi, Alphonse W.; Githinji, Charles G.; Ngeranwa, Joseph N. (International Journal of Pharmacology and Toxicology, 2016)

Inflammation and pain are ubiquitous signs and symptoms of a large number of ailments affecting humanity. There are equally as many methods and substances that are used as remedies for the conditions. Examples of remedies ...
Antinociceptive Activities of Acetone leaf Extracts of Carissa Spinarum in Mice

Mworia, JK.; Gitahi, SM.; Juma, KK.; Njagi, JM.; Mwangi, BM.; Aliyu, U.; Njoroge, WA.; Mwonjoria, KJ.; Mawia, AM.; Nyamai, DW.; Ngugi, MP.; Ngeranwa, JJN. (Medicinal & Aromatic Plants, 2016-10-26)

Despite the progress that has occurred in recent years in the development of therapies for pain, there is still a need for effective and potent analgesics for pain. Pain is defined as unpleasant feeling essential for ...
Antinociceptive properties of dichloromethane: methanolic leaf and root bark extracts of Carissa edulis in rats

Maina, Gitahi S.; Juma, Kelvin.; Maina, Mwangi B.; Muriithi, Njagi J.; Kiambi, Mworia J.; Umar, Aliyu.; Mwonjoria, John K.; Njoroge W., Ann W.; Mburu, David N.; Piero, Ngugi M. (2015-04)

Conventional medications are expensive and arguably associated with various severe adverse effects, hence the need to develop herbal agents that are effective as alternative. Carissa edulis (Forssk.) Vahl is the herb that ...
Antinociceptive Properties of Dichloromethane:Methanolic Leaf Extracts of Caesalpinia volkensii and Maytenus obscura in Animal Models

Maina, Mwangi B.; Maina, Gitahi S.; Muriithi, Njagi J.; Kiambi, Mworia J.; Umar, Aliyu.; Mwonjoria, John K.; Mutero, Ngure G.; Juma, Kelvin K.; Njoroge, Ann W.; Mburu, David.; Piero, Ngugi M. (Pain & Relief, 2015-07-20)

The purpose of physiological pain is protection. Pain is associated with high morbidity and socioeconomic burden. Conventional medication of pain is expensive and arguably associated with various severe adverse effects ...
Association of haemoglobin levels in the first trimester and at 26–30 weeks with fetal and neonatal outcomes: a secondary analysis of the Global Network for Women’s and Children’s Health’s ASPIRIN Trial

S, Jessan; S, Saleem; MK, Hoffman; SS, Goudar; RJ, Derman; JL, Moore; A, Garces; L, Figueroa; NF, Krebs; J, Okitawutshu; A, Tshefu; CL, Bose; M, Mwenechanya; E, Chomba; WA, Carlo; PK, Das; A, Patel; PL, Hibberd; F, Esamai; EA, Liechty; S, Bucher; TL, Nolen; M, Koso-Thomas; M, Miodovnik; EM, McClure; RL, Goldenberg (John Wiley & Sons Ltd., 2021-04-12)

Limited data are available from low- and middleincome countries (LMICs) on the relationship of haemoglobin levels to adverse outcomes at different times during pregnancy. We evaluated the association of haemoglobin levels ...
Biochemical Effects of Sewage Pollution on the Benthic Organism Nerita polita

Munyasya, JN.; Juma, KK.; Burugu, MW.; Mburu, DN.; Okuku, EO (Environmental & Analytical Toxicology, 2015-07-25)

Degradation of coastal ecosystems is an issue of growing concern. Discharges of sewage effluents to sea water is a major contributor to marine pollution. This study examines the biogeochemical effects of sewage pollution ...
Birth weight and gestational age distributions in a rural Kenyan population

Bucher, Sherri.; Nowak, Kayla.; Otieno, Kevin.; Tenge, Constance.; Marete, Irene.; Rutto, Faith.; Kemboi, Millsort.; Achieng, Emma.; Ekhaguere, Osayame.; Nyongesa, Paul.; Esamai., Fabian.; Liechty, Edward. (Research Square, 2022-08-01)

With the increased availability of access to prenatal ultrasound in low/middle-income countries, there is opportunity to better characterize the association between fetal growth and birth weight across global settings. ...
Blood Glucose Lowering Effect and Safety of the Aqueous Leaf Extracts of Zanha africana

Abdirahman, YA.; Juma., KK.; Makori., WA.; Agyirifo, DS.; Ngugi, MP.; Gathumbi, PK.; Ngeranwa, JJN.; Njagi, ENM. (Pharmaceutica Analytica Acta, 2015-09-30)

Zanha africana has been used traditionally to manage many diseases including diabetes, however, its antidiabetic activity and safety is not well evaluated. The aim of this study was to determine in vivo hypoglycemic ...
Caesarean birth by maternal request: a poorly understood phenomenon in low- and middle-income countries

Harrison, Margo S.; Garces, Ana.,; Figueroa, Lester.,; Esamai, Fabian.,; Bucher, Sherri.,; Bose, Carl.,; Goudar, Shivaprasad.,; Derman, Richard.,; Patel, Archana.,; Hibberd, Patricia L.,; Chomba, Elwyn.,; Mwenechanya, Miusaku.,; Hambidge, Michael.,; Krebs, Nancy F. (Oxford University Press, 2020-04-08)
CD38 as Surrogate Marker for HIV Infection in Antiretroviral Naive and Antiretroviral Experienced Patients in Kenya

Njuguna, AN.; Juma, KK.; Waihenya, RK; Mpoke, S.; Mbuchi, M.; Muthami, L; Mathaai, R.; Otieno, P.; Nyakundi, P. (Advances in Molecular Diagnostics, 2016-06-17)

Human Immunodeficiency Virus (HIV) patient management continues to be a challenge all over the world. CD4 absolute counts and viral load are the gold standard tools for monitoring of HIV-1 disease. However, the use of ...
Cesarean birth in the Global Network for Women’s and Children’s Health Research: trends in utilization, risk factors, and subgroups with high cesarean birth rates

Harrison, Margo S.,; Garces, Ana L.,; Goudar, Shivaprasad S.,; Saleem, Sarah.,; Moore, Janet L.,; Esamai, Fabian.,; Patel, Archana B.,; Chomba, Elwyn.,; Bose, Carl L.,; Liechty, Edward A.,; Krebs, Nancy F.,; Derman, Richard J.,; Hibberd, Patricia L.,; Carlo, Waldemar A.,; Tshefu, Antoinette.,; Koso‑Thomas, Marion.,; McClure, Elizabeth M.,; Goldenberg, Robert L. (BMC, 2020-09-15)

Background: The objectives of this analysis were to document trends in and risk factors associated with the cesarean birth rate in low- and middle-income country sites participating in the Global Network for Women’s and ...
Challenges Encounter By Researchers In HIV Research At AMPATH – MTRH On Application Of The Principle Of Justice

Eyinda, Johnstone Milimo; Naanyu, Violet; Kamaara, Eunice (Journal of Public Health, 2018-08)

During research activities there is need to apply ethical principle of justice where justice is about doing what is morally right and proper treatment of persons. It is not easy to maintain justice in research in ...
Clinical signs of possible serious infection and associated mortality among young infants presenting at first-level health facilities

Nisar, Yasir Bin; Tshefu, Antoinette; Longombe, Adrien Lokangaka; Esamai, Fabian; Marete, Irene; Ayede, Adejumoke Idowu; Adejuyigbe, Ebunoluwa A.; Wammanda, Robinson D.; Qazi, Shamim Ahmad; Bahl, Rajiv (PLoS ONE, 2021-06-30)

The World Health Organization recommends inpatient hospital treatment of young infants up to two months old with any sign of possible serious infection. However, each sign may have a different risk of death. The current ...
Concurrent Infections Among Pyretic Children Seeking Treatment at Alupe Sub County Hospital, Busia County, Kenya

Mwongula, Albert W.; Siamba, Donald N.; Mwamburi, Lizzy A.; Mailu, Matilu (European Journal of Applied Sciences, 2023-10-05)

Fever is a frequently occurring medical symptom and may result from many divergent conditions ranging from mild to potentially serious. Children typically get high and fast – occurring fevers, reflecting the effects of ...
COSTS AND COST-EFFECTIVENES OF MANAGEMENT OF POSSIBLE SERIOUS BACTERIAL INFECTIONS IN YOUNG INFANTS IN OUTPATIENT SETTINGS WHEN REFERRAL TO A HOSPITAL WAS NOT POSSIBLE: RESULTS FROM RANDOMIZED TRIALS IN AFRICA

Garg, Charu C.; Tshefu, Antoinette; Longombe, Adrien Lokangaka; Kila, Jean-Serge Ngaima; Esamai, Fabian; Gisore, Peter; Ayede, Adejumoke Idowu; Falade, Adegoke Gbadegesin; Adejuyigbe, Ebunoluwa A.; Anyabolu, Chineme Henry; Wammanda, Robinson D.; Hyellashelni, Joshua Daba; Yoshida, Sachiyo; Gram, Lu; Nisar, Yasir Bin; Qazi, Shamim Ahmad; Bahl, Rajiv (PLOS ONE | https://doi.org/10.1371/journal.pone, 2021-03-15)

Introduction Serious bacterial neonatal infections are a major cause of global neonatal mortality. While hospitalized treatment is recommended, families cannot access inpatient treatment in low resource settings. Two ...
Cultural Adaptation Practices in Health Seeking Behaviour by Caregivers of Mentally Ill Patients in Uasin Gishu County, Kenya

Ombok, Caroline Atieno; Kareithi, Joram; Wandere, Donald (Scientific Research Publishing, 2022-05-27)

For the mentally ill, cultural prescriptions and proscriptions play a major role in their caregiver’s health-seeking behaviour. Most ill patients seek treatment in hospital setting but still, culturally adaptive options ...
A Current Understanding of Alzheimer’s Disease and the Prospects of Phytopharmacological Intervention as a Management Strategy

Juma, KK. (Neurological Disorders, 2015-07-31)

Alzheimer’s disease is a mental disorder that accounts for 60-70% of dementia. Its specific causes have not been determined to date. It is understood as neurodegenerative diseases which progressively gets worse over time. ...
Determination of Hematological Effects of Methanolic Leaf Extract of S. incanum in Normal Mice

Muriithi, Njagi J.; Maina, Gitahi S.; Mugendi, Njagi M.; Maina, Mwangi B.; Kiambi, Mworia J.; Juma, Kelvin K.; Umar, Aliyu; Mwonjoria, John K.; Njoroge, Ann W.; Abdirahman, YA.; Piero, Ngugi M.; Njagi, Eliud NM. (Pharmaceutica Analytica Acta, 2015-10-16)

Medicinal plants and herbs have been used for ages for the purposes of enhancing and maintaining health and organic resistance against body infection. This is due to their ready availability and arguably efficacious ...

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